Genetics-PCB3063 Spring 2008 Home Page
Section 4462- TR 9:35-11:30pm (periods 3 and 4)

Contents:

For course postings, scroll down to the course schedule. You can download Adobe Acrobat Reader (free) to read pdfs.  Likewise, to view powerpoint presentations if you do not have powerpoint you can download a powerpoint viewer (also free).

Lecturer: 

Dr. Edward Braun
Office: Carr 514
Phone: 846-1124
Email: ebraun-AT-zoo.ufl.edu
Office Hours: Tues, 5th period (11:45am-12:35pm) and Wed, 7th period (1:55-2:45pm)

Graduate Teaching Assistants: 

Kin Han, 317 Carr
Email: hankin-AT-ufl.edu
Office Hours: Mon, 10am-noon

Matt Salomon, 619 Carr
Email: msalomon-AT-zoo.ufl.edu
Office Hours: Tues, 1:15-3:15pm

Jena Chojnowski (half time)

Undergraduate Teaching Assistant: 
Tejan Ottallah

Schedule:

Room: Text: Introduction to Genetic Analysis, 9th edition, by Griffiths, Wessler, Lewontin, and Carroll

Exam Schedule:

Grading: Grades will be determined from the three exams, homework, and the papers. There will be NO extra credit.

Determination of grades:

Regrades must be requested in writing, within 7 days of the return of the exam. There will be absolutely no discussion of any grading issues without a written request. Regrades will forfeit any curve that might have been applied to the test, and they should include a detailed explanation - with specific citations (e.g., specific pages in the textbook or specific portions of the class notes) - of why the grade originally given is being contested. Make up exams will not be given except under exceptional circumstances (such as illness or injury); should such circumstances arise, the nature of the exam willbe at the discretion of Dr. Braun.

Grading will be on a percent scale (90%+, A; 86-90%, B+; 80-86% B; 76-80%, C+; 70-76%, C; etc.). A curve may be applied at the discretion of Dr. Braun. This curve will only be applied to increase grades, never to decrease grades.

Honor Code: You are expected to follow the University of Florida honor code. Academic dishonesty of any form will not betolerated. If we are certain that you were cheating or plagiarizing onan assignment, all persons involved WILL receive a zero for therelevant problem set or exam.

Anybody showing up more than 30 min. late to exams MAY be denied the right to take exams. It is your responsibility toknow when exams are scheduled. Any changes in the day of an exam willbe announced at least 7 days ahead of time.

Web Page: The class website is http://www.zoo.ufl.edu/ebraun/PCB3063. Classnotes will be posted on this site weekly (usually by Friday).

Attendance is not required, but material covered only in the lecture WILL appear on exams.

What material am I responsible for? You will be responsible for all material covered in class and for all readings assigned on the schedule (in the readings and problem sets section of the scedule). If the reading is listed as "pp. XX-YY" is refers to a reading from the Griffiths et al. textbook.

The material listed under "Supplementary Material" is NOT explicitly assigned - you will not have to turn it in and it will not be graded. However, it represents practice material for you to work on, so I would recommend you do that work..

Since we are covering material in a different order than in the text, the chapters (and chapter sections, listed as "CHAPTER.SECTION") used as sources for some of the information in the lecture are presented. The chapter reading should be done to HELP you understand the lecture, and they are NOT assigned independently of the lecture. Likewise, the problems are chosen to resemble material on the quizzes. Thus, they are likely to be helpful, but we will not grade them.

TENTATIVE SCHEDULE


 
Week of Topic  Supplementary
Material:

 Chapters
and Problems		 Readings and Problem Sets
7 Jan
Introduction to Genetics - What is a gene?

Biochemical Genetics

[lecture set 1 ppt] [lecture set 1 pdf]

 1.1-1.3
6.1-6.2

Practice Problems:
on pages 28-29
1.2, 1.5, 1.9, 1.10, 1.14
Assigned reading: 

Mitosis and Meiosis
Chapter 2, pp. 42-50

Probability, the chi-square test -
Chapter 3, pp. 94-99

Neurospora as a model system -
Chapter 3, p. 107.
14 Jan Biochemical and Mendelian Genetics, con't
Genomics, Biotechnology

Gels and Blotting
 2.1-2.3
6.1-6.4

Practice Problems:
on pages 121
3.2(10), 3.8(23)

Practice Problems:
on pages 252-253
6.2(2), 6.5(5), 6.6(6)

Note: I am giving you the number for the 8th edition in parens - so 3.2(10) means do problem 2 of chapter 3 in the 9th edition, and that problem 10 of chapter 3 in the 8th edition is the same problem.

 Assigned reading:

Interactions Among Alleles
Chapter 6, pp. 223-235
21 Jan Sex Linkage and Cytoplasmic Inheritance

Organelles, Prions
Quiz 1: Thurs 24 Jan
28 Jan
Cloning and Biotechnology

[lecture set 2 ppt] [lecture set 2 pdf]


[Phe pathway] [BH4 pathway]
[PAH alleles]

[Fungal Phe pathway] [Fungal Phenotypes]

[Practice Test 1] [Quiz 1 Key]

[Practice Test 1 Key]
 20.1-20.3

4 Feb
 Chromosome Structure

Mapping, Lod scores

Bacterial and Bacteriophage Genetics

Conjugation and Transduction

11 Feb TEST 1 - Tues. 12 February 2007
[Test 1 Key]


Transformation

[lecture set 3 ppt] [lecture set 3 pdf]
 
[Practice Test 1]

[Practice Test 1 Key]

Review Session on 11 Feb-- Located in 
Turlington L007  from 5:10pm to 7:05pm
18 Feb Prokaryotic Gene Regulation
The lac operon

25 Feb Transcription in Prokaryotes, con't
The lambda repressor
DNA Structure and Replication


[Additional Prion Information ppt]
[Additional Prion Information pdf]

[lecture set 4 ppt] [lecture set 4 pdf]

3 Mar Eukaryotic Gene Regulation
[Review on Secondary Endosymbiosis]
10 Mar Spring Break
17 Mar TEST 2 - Moved one week to 25 March

Translation, Elucidation of the Genetic Code


[Practice Test 2] [Practice Test 2 Key] 		Recommended Problems:

Chapter 2:
37 through 42

Chapter 3:
23, 34, 38, 41, 44, 48

Chapter 4:
3, 7, 12-14, 20, 25, 26, 28, 33, 34		 Work through the solved problems for chapter 4 (pages 166-168)

Read Section 6.3 (pages 235-239)

Review Session on 24 Mar-- Located in 
NEB 100  from 7:20pm to 8:10pm
24 Mar TEST 2 - Tues. 25 March 2008

[Test 2 Key]

Translation, Genetic Code, con't
31 Mar Transposons, Mutagenesis

[lecture set 5 ppt] [lecture set 5 pdf]
7 Apr Evolutionary Genetics

14 Apr Cancer Biology


[lecture set 6 ppt] [lecture set 6 pdf]
[lecture set 6 large size pdf]

[Practice Test 3] [Practice Test 3 key]

Assigned reading:
    Chapter 14, sections 1, 3 and 4

Review Session on 21 April -- Located in 
MCCA G186  from 6:15pm to 7:30pm
21 Apr TEST 3 - Tues, 22 April 2008